for assistance call: 1-888-673-3444
 
RRRC at Allied Genetics Conference (TAGC24)
 February 20, 2024
Stop by Booth 626 in the Exhibitor Hall at the Allied Genetics Conference (TAGC24) in National Harbor/Washington DC Metro Area on March 6-10, 2024 to discuss how the RRRC can help facilitate your research.

GRCr8: A new rat reference assembly is now available.
 February 05, 2024
GRCr8 (GenBank NCBI # GCA_036323735.1) is the latest version of the rat reference genome assembly. See the Genome Reference Consortium (GRC) blog for more details.
Happy World Rat Day!
 April 04, 2023
April 4, 2023 is World Rat Day!  The RRRC would like to acknowledge the important contributions to science and medicine made possible by the use of rats in biomedical research.
Exciting Job Opportunities
 April 03, 2023
The RRRC is looking to expand its team!  We have positions available in colony management, data curation, cryobiology, reproductive biology, and customer service.  We are also looking for individuals interested in post-doctoral training with both a service and research emphasis.  Interested in learning more?  Contact Dr. Elizabeth Bryda at rrrc@missouri.edu.

NIH Extrinsic Factors Workshop
 August 09, 2022

Enhance Rigor and Reproducibility in Animal Research by Managing Extrinsic Factors

When: September 23, 28, and 30, 2022

Venue: Zoom

Register: scgcorp.com/ExtrinsicFactorsWS

The workshop will be a forum to discuss the current status of and needs for understanding extrinsic environmental factors; their potential impact on animal research outcomes; and how facilities may optimally manage, monitor, and report these extrinsic factors in an effort to enhance reproducibility and rigor in animal research. The focus of this workshop will be on identifying gaps, opportunities, and new approaches in husbandry of commonly and widely used animal models; relevant environmental factors and conditions; and the need for novel instruments, equipment, and infrastructure for animal research core facilities (e.g., modern design of research core facilities, high-throughput equipment, telemetry for behavioral research).

New Models
The RRRC partners with the MU Animal Modeling Core (AMC) at the University of Missouri to generate new rat models of interest and utility to the research community.  If there is a particular rat model that has the potential to be of broad use to the scientific community, please contact us to discuss the possibility of having the RRRC generate this model. 

Examples of Rat Models Generated by the RRRC:

Unpublished but currently available:
RRRC# 938: LE-Rosa26 (CAG-LSL-TdTomato)em1Rrrc

The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats. Chesney KL, Men H, Hankins MA, Bryda EC.(2021) Physiol Genomics. 53:269-281.

Mutational analyses of novel rat models with targeted modifications in inflammatory bowel disease susceptibility genes. Men H, Hankins MA, Bock AS, Beaton BP, Davis DJ, Chesney KL, Bryda EC.(2021) Mamm Genome.32:173-182.

A novel conditional ZsGreen-expressing transgenic reporter rat strain for validating Cre recombinase expression. Bryda EC, Men H, Davis DJ, Bock AS, Shaw ML, Chesney KL, Hankins MA. (2019) Scientific Reports 9:13330.

Rapid conditional ablation model for hemolytic anemia in the rat. Hanson MM, Liu F, Dai S, Kearns A, Qin X, Bryda EC. (2016) Physiological Genomics 48:626-632.

Fischer-344 Tp53-knockout rats exhibit a high rate of bone and brain neoplasia with frequent metastasis. Hansen SA, Hart ML, Busi S, Parker T, Goerndt A, Jones K, Amos-Landgraf JM, Bryda EC. (2016) Dis Model Mech. 9(10):1139-1146.