for assistance call: 1-888-673-3444
 
Weather Advisory
 February 16, 2025
Weather impacts shipments, particularly of live animals. Please check with your selected courier to learn how their shipping methods (e.g. air or ground shipment) and temperature restictions may impact your orders. While we recognize that shipping delays are frustrating, when it comes to live animal shipments, the safety and welfare of the animals comes first. 
In Need of a New Rat Model?
 February 16, 2025
Need a new rat model?  The RRRC in conjunction with the MU Animal Modeling Core (AMC) can assist with the generation of transgenic rats, create knock-out and knock-in rats using CRISPR/Cas9 technology and genetically manipulate rat embryonic stem cells to make chimeric animals.  Contact us to discuss your rat model needs and how we can help. 
Laboratory Animal Genetic Reporting (LAG-R) Guidelines Published
 July 07, 2024
The LAG-R framework (Laboratory Animal Genetic Reporting) is a set of guidelines to support more complete documentation of the genetic make-up of animals of all species that are used in research, with the aim of bolstering reproducibility, reliability, and overall scientific rigor. See Nature Communications (https://doi.org/10.1038/s41467-024-49439-y).
GRCr8: A new rat reference assembly is now available.
 February 05, 2024
GRCr8 (GenBank NCBI # GCA_036323735.1) is the latest version of the rat reference genome assembly. See the Genome Reference Consortium (GRC) blog for more details.
Embryo Culture
he RRRC routinely cultures rat embryos.  We are continually investigating ways to improve culture conditions.  We are available for consultation for investigators who want to work with rat embryos for various applications. In addition, we can supply rat embryos for research purposes as well as generate genetically modified rat embryos for making rat models on a fee-for-service basis.

Some RRRC publications related to rat embryo culture:

KSOM-R supports both mouse and rat preimplantation embryo development in vitro.
Men H, Amos-Landgraf JM, Bryda, EC, Franklin, CL. (2023) Theriogenology 198:69-74.